Radionuclide imaging of bone marrow disorders

The Role of Bone Marrow Aspiration and Bone Marrow Biopsy in Diagnosis of Bone Marrow Metastases

Background: Bone marrow is the site of many malignant disorders and it is one of the common places for solid tumors to metastasize. Examination of the bone marrow aspirate and biopsy is a routine procedure performed for assessment of various conditions such as cytopenias, hematologic neoplasms, nonmalignant disorders and metastatic neoplasms. Methods: The patients were referred to the Hema...

Bone Marrow Imaging

(1) Background Bone marrow is the body’s 4 largest organ constituting 5% of its body weight. It consists of trabecular bone and a variety of cells including hematopoetic, fat, stroma and RES cells as well as sinsusoids. Bone marrow composition changes with age, which is reflected in a change in signal characteristics in MR images. Red marrow, which is found in younger individuals is composed of...

Bone marrow reconversion – imaging of physiological changes in bone marrow

Reconversion of bone marrow is a reverse process of natural replacement of red marrow by yellow marrow. The occurrence of reconversion can be misleading and challenging in interpretation of musculoskeletal system imaging. Changes of signal intensity in bone marrow are frequently observed in radiological routine and its diversity can cause a suspicion of pathologic findings. Therefore, the knowl...

Imaging in Bone Marrow Transplantation.

Bone marrow transplantation (BMT) is a technique used in the treatment of leukemia, lymphoma, aplastic anemia, multiple myeloma, immune deficiency disorders, and certain solid tumors such as breast and ovarian carcinoma. It is a salvage technique that permits high-dose, myelosuppressive chemotherapy to be given, achieving greater response rates to therapy. After giving high-dose therapy, treati...

Bone marrow transplantation for lysosomal storage disorders